DS22-formula is highly effective in the dietary management of various gastrointestinal conditions. Backed by extensive scientific evidence, including over 200 peer-reviewed articles and more than 80 controlled clinical trials, its benefits observed in clinical studies are replicable in daily use.

CDS22-formula 450B is the perfect solution for daily gut flora support. With 450 billion live bacteria per capsule, this formula helps maintain a balanced gut microbiota, which, when disrupted, can lead to occasional digestive discomfort such as bloating or irregular bowel movements. It’s also ideal for seasonal changes that can challenge gut balance.

The De Simone Formulation in CDS22-formula is the only probiotic formulation recommended and recognized by name in the guidelines of the American Gastroenterology Association (AGA) for the management of gastrointestinal disorders (Olleik et al., Gastroenterology, Vol. 164, No. 6, 2023). (Olleik et al., Gastroenterology, Vol. 164, No. 6, 2023).
The European Crohn’s and Colitis Organization (ECCO) has also included the De Simone Formulation i
n its guidelines for managing intestinal disorders (ECCO, ECCO News, 2023).

Benefits

CDS22-formula supports the dietary management of acute and chronic intestinal dysbiosis.

• 450 billion live bacteria per sachet
• 8 well researched bacterial strains
• Managing intestinal dysbiosis- Intestinal dysbiosis is a condition in which the natural balance of microorganisms in the gut is disrupted, leading to a range of gastrointestinal disturbances. Controlling dysbiosis is essential for maintaining digestive balance and improving overall well-being.
• Immediate and long-lasting gut flora restoration – CDS22-formula is ideal for both acute and chronic episodes of intestinal dysbiosis. It is particularly suited to supporting gut flora balance, which, when disrupted, can manifest as temporary or chronic intestinal discomfort. These imbalances may lead to accelerated transit, impacting daily activities and restful sleep.
• Supports Individuals looking to maintain healthy digestion during recurrent or prolonged intestinal stress, including stress linked to emotional well-being.
• Supports Anyone needing to restore or maintain gut flora balance after pharmacological treatments.
• Offers support for IBS, Crohn’s disease, ulcerative Colitis, Diverticulitis, and gastrointestinal infections
• Supports healthy weight management and Blood sugar
• Supports liver health and NAFLD
• Helps with recurrent UTI infections
• Helps with chemotherapy induced diarrhea

• The original formulation- CDS22-formula is the original De Simone Formulation, a unique blend of proprietary bacterial strains designed to maximize its effectiveness in restoring gut flora balance. These strains are cultivated and preserved in proprietary Master Cell Banks, ensuring purity, quality, and consistency in every batch.

Supplement Facts

Product Description: Probiotic Food supplement with 450 billion live bacteria per sachet.

Presentation: 12 sachets of 4.4g

Ingredients:

a blend of live lactic bacteria (Streptococcus thermophilus NCIMB 30438, Bifidobacterium breve NCIMB 30441 , Bifidobacterium animalis subsp. lactis NCIMB 30435, Bifidobacterium animalis subsp. lactis NCIMB 30436, Lactobacillus acidophilus NCIMB 30442, Lactobacillus plantarum NCIMB 30437 , Lactobacillus paracasei NCIMB 30439, Lactobacillus helveticus NCIMB 30440); filling agent: microcrystalline cellulose; hydroxypropylmethylcellulose vegetable capsule; anti-caking agents: fatty acids, magnesium salts of fatty acids.

Average contents per capsule:

Streptococcus thermophilus NCIMB 30438 58 miliardi u.f.c.

Bifidobacterium breve NCIMB 30441 6 miliardi u.f.c.

Bifidobacterium animalis subsp. lactis NCIMB 30435 6 miliardi u.f.c.

Bifidobacterium animalis subsp. lactis NCIMB 30436 6 miliardi u.f.c.

Lactobacillus acidophilus NCIMB 30442 9 miliardi u.f.c.

Lactobacillus plantarum NCIMB 30437 9 miliardi u.f.c.

Lactobacillus paracasei NCIMB 30439 9 miliardi u.f.c.

Lactobacillus helveticus NCIMB 30440 9 miliardi u.f.c.

The content in live cells refers to the product correctly stored in intact packaging, at a refrigerated temperature (+2+8°C), until expiry.

CDS22-formula 450B is gluten-free.

Nutritional Declaration

per 100gper sachet (4,4g)

Energy value 1554 kJ/366 Kcal 68,37 kJ/16,10 Kcal

Fats 0,5 g 0,02 g

of which satured 0,1 g 0,00 g

Carbohydrates 80 g 3,52 g

of which sugars 63 g 2,77 g

Proteins 10 g 0,44 g

Salt 0,28 g 0,01 g

Guaranteed Safety- Each dose undergoes rigorous testing to ensure maximum efficacy and safety. With a short, controlled supply chain approved by the inventor, CDS22-formula upholds the highest quality standards from raw materials to final packaging.

Unmatched value- CDS22-formula offers superior quality at a better price than other probiotics with comparable bacterial concentrations. Efficient production and direct cost control allow us to provide a more affordable solution without compromising quality.

How to use:
Adults and children aged 7 and over: 1-2 sachets per day.
Children from 3 to 6 years: Up to ½ sachet per day.

Instructions for use:
Open the sachet and mix the contents in a fresh non-fizzy drink, yogurt or fruit juice; consume immediately.
For children, the contents of the sachet can be added to fruit compote or yogurt.

Warnings:
Do not exceed the recommended daily dose.
Food supplements are not intended as substitutes for a varied and balanced diet and a healthy lifestyle.
Keep out of reach of young children

Use during pregnancy:
There are no known contraindications of CDS22-formula 450B, but it is advisable to consult your doctor before taking any food supplement during pregnancy. If you are pregnant, breastfeeding, or taking any medications, consult your doctor before using this dietary supplement.

Use during antibiotic therapy:
It is possible to take CDS22-formula 450B in conjunction with antibiotic therapy given the absence of known interactions of these drugs with the bacteria contained in the product. To maximize the beneficial effect of the probiotic, it is advisable to take CDS22-formula 450B a few hours after the drug. If in doubt, ask your doctor or pharmacist for advice.

Side effects:
Although no particular risks associated with the use of CDS22-formula 450B, have been highlighted, the adaptation of the intestinal flora to the bacteria it contains can cause transient abdominal swelling. In this case, it is recommended to reduce the dosage of CDS22-formula 450B for a few days.

In case of serious side effects, reduce the dosage or discontinue use and consult your doctor.

Storage:

Store in the refrigerator to maintain the vitality and potency of the bacteria until expiration.

You can store the product outside the refrigerator at room temperature (up to 25°C) for up to a week without compromising its quality.

Avoid high temperatures (>25°C).

Best before the date indicated on the package.

CDS22-450B

CDS22 Probiotics 450 Billion – 12 Sachets